Researchers from the University of Southampton and the University of Edinburgh examined data from 26 observational studies involving more than 2.25 million participants, finding that one cup more of caffeinated coffee per day was associated with a 20 percent reduction in the risk of developing hepatocellular cancer (HCC). Two cups or more resulted in a 35 percent risk decrease, and five cups resulted in a 50 percent risk decrease.

“We have shown that coffee reduces cirrhosis and also liver cancer in a dose-dependent manner,” said University of Edinburgh Professor Peter Hayes. “Our research adds to the evidence that, in moderation, coffee can be a wonderful natural medicine.”

The researchers said that there was also evidence that drinking decaf had a “beneficial, though less marked” effect. They also pointed to coffee’s proven anti-inflammatory qualities as a potential reason for why coffee is apparently good for the liver.

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